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SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:

1. In a Statistical Analysis Plan (SAP) the following statement is written:
To test the association between the pain intensity reported by the patient and the treatment the patient has been administered, a Cochran-Mantel-Haenszel test will be performed adjusting for the country of the patient's investigational site.
The following variables and levels are used:
- Pain intensity (PAIN): "No pain", "Mild pain", "Moderate pain", "Severe pain", "Most severe pain"
- Treatment group (TREAT): "Placebo", "Drug A", "Drug B"
- Country (COUNTRY): Eight different values.
The following program is written to perform this analysis:
proc freq data=pain;
by COUNTRY;
tables PAIN * TREAT / cmh;
run;
This code does not produce the analysis requested by the SAP.
What is wrong with this code?

A) The variable COUNTRY should be on the TABLES statement instead of the BY statement.
B) The variables PAIN and TREAT should be on the BY statement, and the variable COUNTRY should be on the TABLES statement.
C) The option CMH should be on the PROC FREQ statement instead of on the TABLES statement.
D) The variable PAIN should be on the BY statement along with the variable COUNTRY.


2. What is the key to ensuring traceability across CDISC data sets and modes?

A) Establishing a clear path between an element and all of its immediate successors.
B) Including STDM variables used to derive ADaM variables in the ADaM data set.
C) Establishing a clear path between an element and all of its immediate predecessors.
D) Creating a map for each variable to all of its related predecessors.


3. The following SAS program is submitted:

How many data sets are created and how many observations are in the data set(s)?

A) 2 data sets named PVALUES and PVALUES1 each with 1 observation.
B) 1 data set named PVALUES with 2 observations.
C) 1 data set named PVALUES with 1 observation.
D) 2 data sets named PVALUES1 and PVALUES2 each with 2 observations


4. You are working with the VS data set that contains the variable Pulse.

Which PROC SGPLOT step will produce the graph shown below?

A) proc sgplot data = Work.VS noautolegend;
density pulse;
vbarbasic pulse;
run;
B) proc sgplot data = Work.VS noautolegend;
vbarbasic pulse;
density pulse;
run;
C) proc sgplot data = Work.VS noautolegend;
density pulse;
histogram pulse;
run;
D) proc sgplot data = Work.VS noautolegend;
histogram pulse;
density pulse;
run;


5. Which function would be used to determine the number of elements in an existing array?

A) count ()
B) sum ()
C) dim ()
D) n ()


Solutions:

Question # 1
Answer: A
Question # 2
Answer: B
Question # 3
Answer: A
Question # 4
Answer: A
Question # 5
Answer: C

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